WebJan 28, 2024 · These results place CELF6 in a functional subfamily of CELF proteins that includes CELFs 3, 4, and 5. CELF6 also promotes skipping of exon 11 of insulin receptor, a known target of CELF activity ... WebAug 27, 2024 · CELF6 is an RNA-binding protein in a family of proteins with roles in human health and disease, however little is known about the mRNA targets or in vivo function of this protein.
The natural compound neobractatin inhibits cell ... - ResearchGate
WebJun 19, 2024 · We found the acute response to reward was intact, yet Celf6 mutant mice exhibited impaired conditioned learning to both reward and aversive stimuli. Thus, we found that the resistance to change by the Celf6 mutant in the holeboard was most parsimoniously explained as a failure of conditioning, as the mice had blunted responses even to potent ... WebMar 21, 2024 · CELF6 (CUGBP Elav-Like Family Member 6) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and … filter coffee container
CELF6, a Member of the CELF Family of RNA-binding Proteins, …
WebJun 19, 2024 · Celf6 mutant females exhibited comparable freezing behavior to WT littermates during presentation of the auditory cue on day 3 (Figure 4M). We conducted a meta-analysis of all males from Cohorts 2, 4 and 5 to understand the overall effect of Celf6 loss on contextual and cued fear conditioning. WebJun 29, 2024 · CELF6 overexpression suppressed cell proliferation, cell migration, and cell invasion. Mechanistically, Fructose-Bisphosphatase 1 (FBP1) was identified as the target gene of CELF6 and stabilized by CELF6 via binding 3′UTR. CELF6 overexpression mediated inhibition in TNBC development was dependent on FBP1. Moreover, CELF6 … WebCELF6_HUMAN; CUG-BP- and ETR-3-like factor 6; CUGBP and ETR3 like factor 6; CUGBP Elav-like family member 6; RNA binding protein BRUNOL 6; RNA-binding protein BRUNOL-6; see all. Function. RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are … filter coffee decaf