Perk thr980
WebGSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay. The selectivty is 500-fold higher against a panel of 300 kinases. 体外活性. GSK2656157可抑制小鼠体内多种人移植瘤生长.GSK2656157(50 mg/kg,p.o.)处理8 h后,完全抑制phospho-PERK Thr980. WebPhospho-PERK (Thr980) (16F8) Rabbit mAb RRID:AB_2095853 PDF Report How to cite Antibody Information URL: http://antibodyregistry.org/AB_2095853 Proper Citation: (Cell Signaling Technology Cat# 3179, RRID:AB_2095853) Target Antigen: Phospho-PERK (Thr980) (16F8) Rabbit mAb Host Organism: rabbit Clonality: monoclonal
Perk thr980
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WebPERK as the key kinase regulating eIF2 phosphorylation in vascular endothelial cells. Nextwefoundthat,wheneIF2 wasdepleted(90%knock-down), there was marked suppression of GADD45 under Figure 1. Endorepellin evokes phosphorylation of PERK/eIF2 and up-regulation of ATF-4/GADD45 downstream of VEGFR2. A, representative WebA Life Sciences and Diagnostics business focused on enabling scientists and healthcare professionals to advance research, discovery and detection to improve global health Analytical & Enterprise Solutions An Analytical and Enterprise solutions business, including leading OneSource laboratory services, focused on accelerating scientific outcomes
WebThe Phospho-PERK (Thr980) (16F8) Rabbit mAb Antibody was generated using EIF2AK3 as the antigen. It reacts with Rat. This antibody has been shown to work in applications such as: Western Blot. Phospho-PERK (Thr980) (16F8) Rabbit mAb detects endogenous levels of PERK phosphorylated at Thr980. Phospho-PERK (Thr980) (16F8) Rabbit mAb. Supplier … Web28. nov 2016 · product name : Phospho-PERK (Thr980) (16F8) Rabbit mAb catalog : 3179S quantity : 100 ul price : 274 USD clonality : monoclonal host : rabbit antigen modification : phosphorylated reactivity : human, mouse, rat, pig application : western blot, immunohistochemistry, immunocytochemistry, other more info or order :
Web15. nov 2024 · Formalin-fixed and paraffin-embedded human lung carcinoma labeled with Anti-Phospho-PERK (Thr980) Polyclonal Antibody, Unconjugated (bs-3330R) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated (bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. http://www.tooltest.cn/show-23170.html
Webof PERK (Thr980), IRE1α (Ser724), p38 (Thr180/Tyr182), and c-Jun N-terminal kinases (JNK, Thr183/Tyr185) in atrial tissues contributing to increase in ER stress, which further INFLAMMATION IN AF promotes the production of inflammatory cytokines (Figures 2B,C; Sullivan et al., 2024). Inflammation is one of the major risk factors that has been ...
WebFormalin-fixed and paraffin-embedded human lung carcinoma labeled with Anti-Phospho-PERK (Thr980) Polyclonal Antibody, Unconjugated (bs-3330R) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated (bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. ウィキペディア 方角Web18. jan 2024 · REDD1 expression and PERK phosphorylation at Thr980 were evaluated by Western blotting. Representative blots are shown. Protein molecular mass in kDa is shown at right of blots. B: AC16 cells were exposed to culture medium containing either 5 mM glucose (LG), 25 mM glucose (HG), or HG plus 0.5 mM BSA-conjugated palmitate (PAL) … pagare bollo auto con spidWeb24. nov 2024 · PERK 活性可以通过 Thr980 位点的磷酸化进行监测,PERK 的活性导致 eIF2a 在 Ser51 位点的磷酸化,从而抑制大多数 mRNA 的翻译,但能够诱导关键转录因子 ATF-4。 冠状病毒可诱导转录因子 ATF-6 的激活。 在 ER 应激期间,ATF-6 也从 BiP 上解离,然后转移到高尔基体,在高尔基体中它被蛋白酶激活。 通过 BiP 结合错误折叠蛋白的累积可以直 … pagare bollo auto aziendaleWebProtein kinase-like endoplasmic reticulum kinase (PERK) is an eIF2α kinase and transmembrane protein resident in the endoplasmic reticulum (ER) membrane that … pagare bollo auto con f24WebThe secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed. Blank control: A431. Primary Antibody (green line): Rabbit Anti-PERK (Thr980) antibody (bs-3330R) Dilution: 3μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody: Goat anti-rabbit IgG-AF647. pagare bollo auto con cbillWebWestern blot using Phospho-PERK (Thr980) Monoclonal Antibody (G.305.4) (Product # MA5-15033), shows induction of protein in RSC96 upon Thapsigargin and Tunicamycin … ウィキペディア 編集Web29. júl 2024 · Expression of ER stress and UPR markers in HUVECs exposed to clinorotation for 48 h. Western blot analysis of p-PERK (Thr980), p-EIF2S1 (Ser51), CHOP, ATF6, GRP78 and p-IRE (Ser724) under clinorotation for 48 h or … pagare bollo agenzia entrate