Thrap3 gene
WebShowing subcellular location of THRAP3 (BCLAF2, TRAP150). We use cookies to enhance the usability of our website. ... THRAP3: Gene description i. Thyroid hormone receptor associated protein 3: Protein class i Plasma proteins: Predicted location i. Intracellular: Number of transcripts i. 3: HUMAN ... WebMutations in the FOXP3 gene lead to severe autoimmunity and inflammation in both mice and humans 1,2. ... SPEN, THRAP3, and VDR have not been previously associated with eTreg cell differentiation.
Thrap3 gene
Did you know?
http://genesdev.cshlp.org/content/28/21/2361.full.pdf WebIn chromatin immunoprecipitation assays, endogenous Helz2 and Thrap3 could be co-recruited, in a ligand-dependent manner, to the PPARγ-response elements in Fabp4/aP2 and Adipoq gene enhancers in differentiated 3T3-L1 cells. These findings collectively suggest that Thrap3 could play indispensable roles in terminal differentiation of adipocytes ...
WebOct 25, 2024 · Thrap3 colocalizes with R-loops, and Thrap3 depletion leads to R-loop accumulation. Thrap3 is an RNA-binding protein related to the DNA damage response … WebDec 2, 2024 · Gene ID: 256643, updated on 29-Mar-2024. Download Datasets Summary. Go to the top of the page Help. Official ... BCLAF1 and THRAP3 family member 3 provided by HGNC Primary source HGNC:HGNC:27413 See related Ensembl:ENSG00000173681 AllianceGenome:HGNC:27413 Gene type protein coding
WebWe also asked whether Thrap3 controls diabetic gene programming in vivo. As shown in Figure 5A, treatment with Thrap3 ASO in high-fat-fed mice caused changes in the expression of nine out of 17 of the diabetic genes that are significantly controlled by CDK5 action on PPARγ (Choi et al. 2010). WebTHRAP3 is a 955 amino acid novel nuclear receptor and a member of the Thyroid hormone receptor associated proteins with a LISH domain and no obvious known sequence motifs. THRAP3 is a 150 kDa subunit of the large multiprotein complex TRAP and is important in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar …
WebOct 1, 2024 · Therefore, it is important to understand how PPARγ is regulated. Thyroid hormone receptor-associated protein 3 (THRAP3) was previously reported to promote diabetic gene expression by acting as a transcriptional coregulator of PPARγ in adipocytes. Therefore, we tested if THRAP3 modulated anti-inflammatory functions of PPARγ in 3T3 …
WebMar 21, 2024 · anti-THRAP3P1 antibody (Thyroid Hormone Receptor Associated Protein 3 Pseudogene 1) N-Term. Browse Primary Antibodies and Browse Secondary Antibodies. … song red rubber ball youtubeWebNational Center for Biotechnology Information smallest wireless eaWebCensus tier 2. This is a putative cancer gene, from Tier 2 of the Cancer Gene Census . Tier 2 genes have strong indictations of a role in cancer. Curated gene. This is NOT an expert … song redbone by childish gambinoWebApr 8, 2024 · GSK3A-or THRAP3-knockdown (KD) HCT116 or DLD-1 cell lines were generated using a CRISPR/Cas9 system. There were two gRNAs targeting the human GSK3A gene and two gRNAs targeting the human THRAP3 gene. The HCT116 and DLD-1 cells after knockdown of the target genes were screened by puromycin (ST551, Beyotime). song red house jimi hendrixWebInteracts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA. Component of the SNARP complex which consists at least of SNIP1, SNW1, THRAP3, BCLAF1 and PNN. Component of a MACOM-like complex, named WTAP complex, composed of WTAP, ZC3H13, CBLL1, KIAA1429, RBM15, BCLAF1 and THRAP3. song red red robinWebCell type proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions … song rednecks white sockssong red sails in sunset by fats domino play